![]() The Hooker Imaging Core makes available instruments based on light microscopy and transmission electron microscopy (TEM) and some TEM sample preparation services. Electron Microscopy Chapel Hill Analytical and Nanofabrication LaboratoryĬHANL ( Chapel Hill Analytical and Nanofabrication Laboratory) is a core facility at the University of North Carolina at Chapel Hill that enables cutting edge research by providing equipment, expertise and training for nano/micro fabrication and characterization in an open-access facility with capabilities not otherwise available on campus. This core facility also features two high-end workstations (512GB of RAM, 12 and 14 Cores each, and multiple powerful GPUs) custom-designed for efficient processing and analysis of very large data sets. In addition to providing access to high resolution imaging technologies, the Microscopy Core also implements new imaging technologies, and provides training, consultation, data analysis, image processing, and centralized technical expertise to support the imaging needs of scientists in the UNC community. The Core also features widefield fluorescence and color imaging microscopes that can perform integrated analysis and acquisition for high content imaging experiments and can image tissues in live animals in situ with macro to micro imaging resolution. These single photon confocals are complemented by a two-photon microscope set-up for imaging of live animals and large fixed tissues with high resolution optical sectioning. The Core has multiple state-of-the-art confocal microscopes that are equipped for fast and high-resolution scanning of large areas with tiling and stitching capabilities, imaging live cells and tissues with incubation and CO2, and super-resolution and deconvolution modules for high-resolution imaging. The Neuroscience Microscopy Core provides a full spectrum of advanced systems for cellular and molecular imaging of in vitro and in vivo samples. A significant effort is devoted to training investigators who require microscopy techniques to advance their projects The Neuroscience Microscopy Core Facility Trained users work independently with on-site support. For the infrequent, untrained user, the Imaging Facility provides a completely assisted technical support service. The Hooker Imaging Core is open to all users in the University and Corporate community on a fee basis. There is also a transmission electron microscope with sample preparation services with training available. The high resolution light microscopy systems are now augmented with a Zeiss Airyscan super-resolution sensor. The Hooker Imaging Core is a research facility providing state-of-the-art confocal and wide-field microscopy systems. Tiling, multi-day live-cell experiments, FRAP, FRET, spectral imaging and other experimental designs are available The Hooker Imaging Core Facility We have experience with confocal, light-sheet, widefield fluorescence, darkfield, and polarization microscopy. The Microscopy Services Laboratory will consult with you about your project, advise on experimental design and sample preparation, and train you to take images. It has two components: Electron Microscopy and Light Microscopy. ![]() The Microscopy Services Laboratory is a cost recovery center open to all UNC researchers. These methods can be used on specimens ranging from molecules to cells to whole animals including humans. The UNC Imaging Cores and Resources Page introduces a range of methodologies available on Campus ranging from light and electron microscopy to flow cytometry to image analysis techniques. These are brief profiles of the cores to find more detailed information on each core, including location, contact information, and equipment lists, please check out their facility overview in their listing in our searchable database. These pages list our core facilities by areas of focus. 8.4 Computer Integrated Systems for Microscopy and Manipulation (CISMM).8.3 Chapel Hill Analytical and Nanofabrication Lab (CHANL).8.2 Biomedical Research Imaging Center (BRIC): Image Storage and Analysis.8.1 Bioinformatics and Analytics Research Collaborative (BARC).6.2 Intellectual and Developmental Disabilities Center Clinical Translational Core. ![]() 6.1 Biomedical Research Imaging Center (BRIC): Human Imaging Facility.5.1 Biomedical Research Imaging Center (BRIC) Small Animal Imaging Facility (SAIF).2.1 Chapel Hill Analytical and Nanofabrication Laboratory.1.3 The Neuroscience Microscopy Core Facility.
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